Added: Edgardo Burchfield - Date: 18.11.2021 15:39 - Views: 29845 - Clicks: 9918
Marijuana is known to cause symptoms suggestive of orthostatic hypotension such as dizziness and fainting during upright posture. We examined changes in cerebral blood velocity CBV and peripheral circulation during upright posture after smoking marijuana in 10 right-handed male subjects with a history of exposure to marijuana. The participants were physically and mentally healthy and drug-free for a minimum of 3 months before the experiment.
Middle cerebral artery CBV, blood pressure and pulse rate were recorded during reclining position and standing, before and after smoking a high-potency marijuana cigarette or a placebo cigarette administered during 2 separate visits to the laboratory. The participants were questioned about dizziness during the upright position.
Six of 10 subjects reported moderate to severe dizziness during standing after marijuana but not placebo. Subjects who experienced severe dizziness during standing showed marked decreases in blood pressure and CBV. Those who reported moderate dizziness showed reduction in CBV but not blood pressure. Subjects who reported mild dizziness after marijuana and after placebo smoking showed minimal changes in blood pressure and CBV. Cerebral ischemia during upright position after marijuana smoking may be caused by hypotension and impaired cerebral autoregulation.
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Optional text in :. Save Cancel. Create a file for external citation management software Create file Cancel. of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Full text links Cite Display options Display options. Abstract Marijuana is known to cause symptoms suggestive of orthostatic hypotension such as dizziness and fainting during upright posture. Similar articles Changes in middle cerebral artery velocity after marijuana. Mathew RJ, et al. Biol Psychiatry. Postural syncope after marijuana: a transcranial Doppler study of the hemodynamics.
Pharmacol Biochem Behav. Increased impedance to inspiration ameliorates hemodynamic changes associated with movement to upright posture in orthostatic hypotension: a randomized blinded pilot study. Melby DP, et al. Heart Rhythm. Epub Oct Initial orthostatic hypotension is unrelated to orthostatic tolerance in healthy young subjects. Thomas KN, et al. J Appl Physiol Epub Jun PMID: Cerebral autoregulation in orthostatic intolerance. Schondorf R, et al. Ann N Y Acad Sci. PMID: Review. See all similar articles.
Moustafa B, Testai FD. Moustafa B, et al. Curr Neurol Neurosci Rep. A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates. Reece AS, et al. BMC Cancer. Neurotoxicology Syndromes Associated with Drugs of Abuse.
Caplan RA, et al. Neurol Clin. Latif Z, Garg N. Latif Z, et al. J Clin Med. Ladha KS, et al. Cannabis Cannabinoid Res. See all "Cited by" articles. Publication types Comparative Study Actions. Research Support, U. Gov't, P. MeSH terms Adult Actions. Humans Actions. Male Actions. Placebos Actions. Substances Placebos Actions. Related information MedGen. Full text links [x] Wiley. Copy Download.Can you faint from smoking weed
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Why Does Cannabis Make Me Faint?